Age-dependent modulation of motor network connectivity for skill acquisition, consolidation and interlimb transfer after motor practice

Age-related differences in neural strategies for motor learning are not fully understood. We determined the effects of age on relationship between network connectivity and skill acquisition, consolidation, interlimb transfer using dynamic imaging coherent sources. Healthy younger (n = 24, 18–24 y) older 65–87 adults unilaterally practiced a visuomotor task resting-state electroencephalographic data was acquired before after practice as well at retention. The results showed that right-hand acquisition consolidation did differ groups. However, affected ability to newly non-practiced limb. Moreover, strengthened left- right-primary cortex-related beta negatively positively associated with left-hand adults, respectively. Age-dependent modulations bilateral indicate age-specific novel tasks. present provide insights into mechanisms underlying important development interventions patients unilateral injuries.